Instructions for posters:
- Authors of posters are totally free in the design of their posters.
- The size of the poster should not exeed the format A0 tall (width 84,1 cm x height 118,9 cm).
- The posters will be presented throughout the congress.
- This will allow participants to read the posters during coffee breaks.
- There will be two special poster sessions – one on Tuesday (27.9.2022) and one on Wednesday (28.9.2022).
- The posters will be divided into two groups.
- During the poster sessions the poster authors must be present directly at the poster.
Poster session 1: Tuesday, 27.9.2022, 14:00 – 15:30, first floor
| Poster number | Title | Authors |
| 1 | Investigation of ADHD-associated alterations of the neurovascular unit by aid of hiPSC-derived in vitro models | Markus Glaser, Zora Schickardt, Sabrina Oerter, Rhiannon McNeill, Carolin Koreny, Christian Lotz, Sarah Kittel-Schneider, Antje Appelt-Menzel |
| 2 | Identifying skin sensitizers with an innervated 3D-skin model | Wiebke Bergforth (YSTA), Maren Schenke, Bettina Seeger |
| 3 | Rational design and evaluation of electrospun scaffolds as cell culture substrates for the cultivation of human induced pluripotent stem cells | Felix Rohde (YSTA), Karin Danz, Nathalie Jung, Sylvia Wagner, Maike Windbergs |
| 4 | Penetration of topical aminophosphonates through the dermal barrier – “skin-on-a-chip” development with an emphasis on animal number reduction | Dorottya Kocsis (YSTA), Rusul Keshwan, Franciska Erdő |
| 5 | Dry powder aerosols crossing the pulmonary barrier in vitro – Powder Atomizer aims for predicting human pharmacokinetic profiles | Marius Hittinger, Janina Osti, Annika Dehne, Sarah Wengschick, Thorsten Preisegger, Daniel Primavessy, Marielle Fink, Marc Mamier, Tobias Krebs |
| 6 | Characterization of human brain endothelial cells for the development of in vitro blood-brain barrier models. | Natascha Santacroce, Floriana Burgio, Laura Suter-Dick |
| 7 | Immunocompetent 3D model of human airways as predictive tool for clinical outcomes | Martina Di Fede, Giulia Realini, Bruna Clemente, Serena Tondi, Marianna Taccone, Sonia Budroni, Martina Canè, Andrea Ariolli, Kevin Pete Buno, Francesca Schiavetti, Michela Brazzoli, Daniela Rinaudo, Isabel Delany, Raffaella Cecchi, Tommaso Pasquali, Shahjahan Shaid, Silvia Rossi Paccani, Alfredo Pezzicoli |
| 8 | Using an innovative in vitro platform to investigate the early effects of oxidative stress and increased pressure on human trabecular meshwork cells. | Sara Tirendi, Anna Maria Bassi, Vanessa Almonti, Sonia Scarfì, Mario Passalacqua, Stefania Vernazza |
| 9 | Interaction and transport of small extracellular vesicles across human biological barrier in vitro models | Adrián Klepe, Ana Špilak, Sophia Theresa Kriwanek (YSTA), Andreas Brachner, Christa Nöhammer, Winfried Neuhaus |
| 10 | Animal-Free Plant-Derived Nanofibrillar Cellulose Hydrogels for Cell-Based Assays with Stem Cell and Organoid Cultures | Lauri Paasonen, Essi M. Niemi, Jonathan Sheard, Tony Kiuru |
| 11 | Humanized 3D cell culture materials – the next generation of in vitro testing | Catarina Custódio, Inês Deus, Cátia Monteiro, Sara Santos, João Mano |
| 12 | Human platelet lysate as a replacement for fetal bovine serum in biological barrier in vitro models | Andreas Brachner, Christina Gruber, Malgorzata Burek, Anja Neuhoff, Claudia Bernecker, Peter Schlenke, Winfried Neuhaus |
| 13 | Using perinatal tissues as a sustainable source of xeno-free platforms for cell culture | Inês Araújo Deus (YSTA), Catarina Almeida Custódio, João Filipe Mano |
| 14 | Fostering Awareness, Accessibility, and Acceptance of Animal-Free Antibodies | Niamh Haslett, Michael Cook, Jesus Calvo-Castro, Stewart Kirton, Jarrod Bailey |
| 15 | Lysosomal trapping measurement in multiple cell types using High Content Screening System | Johanna Pacsuta, Katalin Jemnitz, Gábor Nagy, Zsuzsanna Gáborik |
| 16 | Risk assessment of medical devices for the oral cavity using a human oral mucosa epithelium model | Ana Špilak, Peter Pôbiš, Lada Svobodová, Alena Moulisová, Andreas Brachner, Markéta Dvořáková, Helena Kandarova, Dagmar Jirová, Kristina Kejlová, Winfried Neuhaus |
| 17 | Landscape New Approach Methodologies (NAMs) for safety assessment of chemical substances | Victoria C. de Leeuw, Jelle Vriend, Lianne de Wit-Bos, Jacqueline van Engelen, Anne Kienhuis |
| 18 | Effects of nanoplastics on cells of the neurovascular unit | Aleksandra Chmielewska, Marie-Therese Leiningen-Westerburg, Lukas Wimmer, Lea Ann Dailey, Malavika Manju Sudheer, Despina Fragouli, Ana Špilak, Andreas Brachner, Winfried Neuhaus |
| 19 | Generation of reporter models for rapid oxidative stress induction measurement in vitro and application to 3D bronchial tissue cultures | Marion Alriquet, Giulia Fonti, Karsta Luettich, Marco van der Toorn, Stefan Frentzel, Joanne Chua |
| 20 | Use of organotypic gingival cultures for the assessment of nicotine pouches | Filippo Zanetti, Marion Alriquet, Laura Ortega Torres, Laurent Neau, Fabio Maranzano, Claudius Pak, Amandine Schmutz, Carole Mathis, Nazan Gunduz, Joanne Chua |
| 21 | Reducing the number of controls in fish early life stage toxicity tests when solvents are used | Christopher Faßbender, John W Green, John Handley, Thomas H Hutchinson, Lennart Weltje, Daniel Faber, Gilly Stoddart |
| 22 | Evaluation of the cytotoxic and inflammatory effect of two size-separated fractions of Russian chrysotile asbestos fibre | Serena Mirata, Vanessa Almonti, Stefania Vernazza, Dario Di Giuseppe, Alessandro F. Gualtieri, Anna Maria Bassi, Sonia Scarfì |
| 23 | Evaluating the toxicity of sea-dumped conventional and chemical munitions to fish and human cells using a combination of cell viability assays | João Barbosa, Colin R Janssen, Jana Asselman |
| 24 | Optimization of skin sensitization testing strategy in vitro for medical device extracts | Lada Svobodová, Marian Rucki, Alena Vlkova, Kristina Kejlova, Dagmar Jirova, Hana Kolarova |
| 25 | Prediction of human toxicology with alternative experimental models – zebrafish embryo (EU project PrecisionTox) | Stefan Scholz, Riccardo Massei |
| 26 | Risk assessment of microplastic by in vitro genotoxicity assays | Clemens Rausch, Elisabeth Simböck |
| 27 | Hormonal influence on the primordial germ cell proliferation and distribution in the early development of the Medaka | Leonie Hobohm, Lukas Strobel, Annika Pätzold, Alexander Froschauer |
| 28 | Effects of Plastic on the reproductive behaviour of the freshwater snail Biomphalaria Glabrata: an invertebrate in vivo study | Linda Prähauser, Robin Friedrich, Nevena Lakic, Karoline Schweitzer, Christoph Olscher, Xavier Monforte, Barbara Gepp, Elisabeth Simböck |
| 29 | Use of Assay Ready KeratinoSens® Cells to test for Skin Sensitization | Lukas Focke, Valerie de Boor, Andreas Natsch, Oliver Wehmeier |
| 30 | Refinement of an in vitro testing battery for developmental neurotoxicity assessment by integration of radial glia- and astrocyte-specific endpoints | Etta Zühr, Katharina Koch, Ellen Fritsche |
| 31 | Cross-species-relevance of in vitro bioassay battery for the assessment of thyroid hormone disruption | Jiri Novak, Puja Kumari, Runze Liu, Klara Hilscherova |
| 32 | Proteomics reveals mechanisms of metabolic disruptive effects of emerging di-(2-ethylhexyl) phthalate substitutes | Alexandra Schaffert, Isabel Karkossa, Elke Ueberham, Rita Schlichting, Katharina Walter, Josi Arnold, Matthias Blüher, John T. Heiker, Jörg Lehmann, Martin Wabitsch, Beate I. Escher, Martin von Bergen, Kristin Schubert |
| 33 | Cell type and developmental time-dependent effects of genotoxins on neural stem-/progenitor cell functions in vitro | Melanie Pahl, Jördis Klose, Ellen Fritsche |
| 34 | Retrofitting in vitro test systems for high throughput screening of thyroid disrupting chemicals with external biotransformation systems – a critical review and tiered in vitro/in silico approach | Sebastian Lungu-Mitea, Andreas Schiwy, Felipe Vidal, Inska Reichstein, Puja Kumari, Miriam N. Jacobs, Klara Hilscherova |
| 35 | Development of the NPC1ab_RAR_GR assay, an in vitro test method to identify putative endocrine disrupting chemicals (EDCs) perturbing glucocorticoid receptor (GR) or retinoic acid receptor (RAR) signaling | Kevin Schlüppmann (YSTA), Saskia Hüsken, Louisa Stark, Arif Dönmez, Eike Keßel, Nils Förster, Katharina Koch, Ellen Fritsche |
| 36 | Mitochondrial toxicity; AOP-driven extrapolation from in vitro/in silico data to regulation | Wanda van der Stel, Giada Carta, Julie Eakins, Johannes Delp, Ilinca Suciu, Anna Forsby, Andrea Cediel-Ulloa, Kristina Attoff, Florentina Troger, Hennicke Kamp, Iain Gardner, Barbara Zdrazil, Martijn J.Moné, Gerhard F. Ecker, Manuel Pastor, Jose Carlos Gómez-Tamayo, Andrew White, Erik H. J. Danen, Marcel Leist, Paul Walker, Paul Jennings, Susanne Hougaard Bennekou, Bob van de Water |
| 37 | A xeno-free in vitro 3D synovial membrane model mimicking the pathogenesis of arthritis | Julia Beißel, Christina Lubahn, Duc Ha Do Nguyen, Moritz Pfeiffenberger, Frank Buttgereit, Timo Gaber, Alexandra Damerau |
| 38 | Fluidic shear stress reduces TNFα-mediated cartilage damage in a 3D model of degenerative joint disease | Christina Lubahn, Julia Beißel, Duc Ha Do Nguyen, Moritz Pfeiffenberger, Thomas Leeuw, Frank Buttgereit, Timo Gaber, Alexandra Damerau |
| 39 | VHP4Safety: Assessing the safety of chemicals and pharmaceuticals without using laboratory animals | Anne S. Kienhuis, Cyrille A.M. Krul, Juliette Legler and the VHP4Safety consortium |
| 40 | Twinning towards excellence in alternative methods for toxicity assessment – TWINALT project | Zuzanna Sobańska, Joanna Roszak, Tamara Vanhaecke, Maria Dusinska, Elise Rundén-Pran, Marina Marinovich, Edyta Reszka |
Poster session 2: Wednesday, 28.9.2022, 14:00 – 15:30, first floor
| Poster number | Title | Authors |
| 41 | A mouse pup model for learning the Phalanx Distalis Amputation and pup handling | Maximilian Nuber, Miriam Priester, Nadine Baumgart, Jan Baumgart |
| 42 | The role of the Animal Welfare Body in ensuring compliance with the 3Rs: a case study of the forced swim test | Kimberley Jayne, Julia Baines, Emily R Trunnell |
| 43 | Target group specific efforts to facilitate replacement of animal experimentation | Lisa Andersson, Kaisa Askevik, Elvira Hukasova, Emma Svensk |
| 44 | Transforming Culture: Culture of Care in Animal Research | Katharina Ameli,, Stephanie Krämer |
| 45 | Antibodies: Resistances to overcome on the way to a cruelty-free future | Johanna Walter, Tamara Zietek, Corina Gericke |
| 46 | Modernizing Medical Research to Benefit People and Animals | Isobel Hutchinson, Carla Owen, Jarrod Bailey |
| 47 | Knowledge, skills, attitudes and beyond | Nick D. Jukes |
| 48 | How to address animal methods bias in scientific publishing | Catharine E. Krebs, Helder Constantino, Lilas Courtot, Kathrin Herrmann, Ann Lam, Sofia Batista Leite, Janine McCarthy, Brinda Poojary, Kristie Sullivan |
| 49 | Attitudes towards animal dissection and animal-free alternatives among high school biology teachers in Switzerland | Miriam A. Zemanova, Silvia Frey |
| 50 | TPI.tv: A visual platform for animal-free innovations | Victoria C. de Leeuw, Harm J. Heusinkveld, Anne S. Kienhuis |
| 51 | ReThink3R 2.0 Summer School – Educating the next generation of scientists | Annemarie Lang, Lisa Grohmann,Katharina Hohlbaum, Philipp Burt, Alexandra Damerau, Marcel Bermudez, Moritz Pfeiffenberger, Laura Behm |
| 52 | Animal and Tissue Exchange platform (ATEX) | Jan van der Valk, Daan Weustenraad, Wim de Leeuw |
| 53 | Knowledge and Attitude Towards laboratory animals use and 3Rs: A cross-Sectional Study in Sudan | Ahmed Algali, Abednego N. Masai, Fadlalbaseer A. E. Alnoor, Saeed S. A. Ahmed, Ragda A. A. Mohammed, Ali A. Saeed, Banu C. Tel |
| 54 | Combining antiviral, anti-inflammatory and antibacterial properties of drugs in fighting COVID-19 disease | Jana Viskupičová, Petronela Rezbárikova, Marta Šoltesová Prnová, Helena Kandarova, Magdalena Májeková1 |
| 55 | Establishment of a human Synovium-on-a-chip for osteoarthritis disease-modeling using animal-free technologies | Eva I. Reihs (YSTA), Reinhard Windhager, Stefan Toegel, Hans P. Kiener, Peter Ertl, Mario Rothbauer |
| 56 | Single Cell Sequencing To Study IL-1β Induced Changes In Chondrocyte Pellet Cultures | Sebastian Kurmies (YSTA), Antje Vester, Marta Ferreira-Gomes, Gabriela M. Guerra, Frederik R. Heinrich, Carl C. Götzke, Vikram Sunkara, Pawel Durek, Joel D. Boerckel, Mir-Farzin Mashreghi, Annemarie Lang |
| 57 | A human in vitro model for airway epithelial injury and regeneration | Ashesh Chakraborty (EPAA student grantee), Michal Mastalerz, Hannah Marchi, Raphael Meixner, Rudolf A. Hatz, Jürgen Behr, Michael Lindner, Anne Hilgendorff, Claudia A. Staab-Weijnitz |
| 58 | Human-derived in vitro test systems of inflammatory bowel diseases as an alternative to laboratory animal models | Spyridon Damigos, Christina Fey, Nicolas Schlegel, Marco Metzger, Daniela Zdzieblo |
| 59 | Advanced in vitro models to study molecular mechanisms of Alzheimer’s disease | Zahra Motamed, Carine Gaiser, Laura Suter-Dick |
| 60 | Cultivation of Human Skin Biopsies for Preclinical Testing on human trabecular meshwork cells. | Astrid Wurbs, Katrin S. Wallner, Clemens Kittinger, Georg Singer, Beate Rinner |
| 61 | Enhanced drug metabolisms of hepatocytes with physiological aerobic respiration enabled by a new oxygen-permeable plate as an alternative culture format | Yasuyuki Sakai, Masaki Nishikawa, Hiroyasu Ito, Fumiya Tokito, Mathieu Danoy, Takumi Kawanishi, Hiroshi Arakawa, Yukio Kato, Tomoaki Matsugi, Jingjing Yang, Katsuhiro Esashika, Toru Sumita |
| 62 | Vitamins’ B6 and C enhance the huIFN-αn3 induction by the NDV ZG1999HDS or Sendai virus | Bratko Filipič, Lidija Gradišnik, Adriana Pereyra, Hrvoje Mazija |
| 63 | Direct Replacement of Secondary Antibodies by Affimers | Isobel Gibson |
| 64 | Neutralising effects of different antibodies on Clostridioides difficile toxins TcdA and TcdB in a translational approach | Georg Csukovich (YSTA), Nina Kramer, Barbara Pratscher, Ivana Gotic, Patricia Freund, Rainer Hahn, Gottfried Himmler, Sabine Brandt, Iwan A Burgener |
| 65 | High throughput intestinal tissues and on newly fabricated 96-well culture plates | Zachary Stevens, Paul Kearny, Mitch Klausner, Alex Armento, Marek Puskar, Seyoum Ayehunie |
| 66 | Human placental villous tissue explants as basis for 14-day toxicity studies | André Schmidt, Enora Flache, Astrid Schmidt, Nora Schulz, Maren Klett, Merle-Johanna Küstner, Frank Weise, Jörg Hampl, Gregor Schlingloff, Andreas Schober, Udo R. Markert |
| 67 | Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids | Tomas Smutny, Veronika Bernhauerova, Lucie Smutna, Jurjen Duintjer Tebbens, Petr Pavek |
| 68 | Implementing microfluidic systems into the 2D and 3D cultures: challenges and benefits of the flow | Peter Pôbiš, Helena Kandarova |
| 69 | 3D lung-organoid platform for the identification of pharmaceutical compounds targeting senescence and inflammation | Michelle Brand, Felix Ritzmann, Deivydas Milasius, Yiwen Yao, Rolf Müller, Robert Bals, Daniela Yildiz, Christoph Beisswenger |
| 70 | Differentiation of specialized epithelial cells in porcine intestinal organoids | Judith Lehmann, Maren Schenke, Bettina Seeger |
| 71 | Antibiotics free nanoformulations for treatment of non–healing wounds | David O. Oluwole, Lucy Coleman, William Buchanan, Tao Chen, James Adams, Roberto M. La Ragione, Lian X. Liu |
| 72 | Development, efficacy and safeyt of a novel therapeutic protocol against an eperimental models of human malignant melanoma | Anestopoulos Ioannis, Paraskevaidis Ioannis, Tragkola Venetia, Kyriakou Sotiris, Panayiotidis Mihalis |
| 73 | Anti-hyperglycemic, anti-hyperlipidemic, anti-inflammatory and antioxidant activity of Amachol®, an aqueous amaranth seed extract, using a human small intestinal organotypic culture model | Sonia Scarfì, Stefania Vernazza, Serena Mirata, Jan Markus, Silvia Letasiova, Alessia Mattiello, Roberto Premoli, Anna Maria Bassi, Mirko Magnone |
| 74 | Use of Assay Ready THP-1 derived macrophages to test for pyrogen contamination | Adrian Dittberner, Lukas Focke, Mirta Jacobs, Karen Hinsch |
| 75 | Evaluation of ocular side effects of systemically adminstered medications using the in vitro reconstructed human corneal epithelial tissue model | Yulia Kaluzhny, Mitchell Klausner, Viktor Karetsky, Alex Armento, Marek Puskar |
| 76 | International Project Train-SafeMDs: Towards the development of an in vitro testing strategy for local tolerance testing of medical devices used in the oral cavity | Helena Kandarova, Dagmar Jírová, Winfried Neuhaus, Kristína Kejlová, Markéta Dvořáková, Lada Svobodová, Alena Moulisová, Marian Rucki, Ana Špilak, Peter Pôbiš1 |
| 77 | Evaluation of phototoxic potential and ability to form ROS of selected compounds by using EpiDermTM Phototoxicity test | Martina Nalezinkova, Lenka Hudecova, Jan Markus, Silvia Letasiova |
| 78 | Ex vivo platform for feeding of ticks | Matěj Kučera, Tereza Hatalová, David Hartmann, Jan Perner |
| 79 | A Promising Method for the Determination of Cell Viability: The Membrane Potential Cell Viability Assay | Eneko Madorran, Andraž Stožer, Zoran Arsov, Uroš Maver, Jan Rožanc |